CA 125 Test: Diagnostic Pathology, Uses, and Results

The CA 125 test is a blood test used to measure the levels of CA 125 protein in the blood. CA 125 is a protein that is often found at higher levels in women with ovarian cancer.

However, it is important to note that elevated CA 125 levels can also be caused by other conditions such as endometriosis, uterine fibroids, and pelvic inflammatory disease.

The CA 125 test is not used as a definitive diagnostic tool for ovarian cancer but is rather used in conjunction with other tests and imaging studies to help in the diagnosis and monitoring of ovarian cancer.

The test involves taking a blood sample from a vein in your arm, which is then sent to a laboratory for analysis. Results are typically available within a few days.

It is important to note that CA 125 levels can also be elevated in non-cancerous conditions, so a high CA 125 level does not necessarily mean that a person has ovarian cancer.

Conversely, some women with ovarian cancer may have normal CA 125 levels.

What is the Purpose of Performing a CA 125 test Test?

The primary purpose of performing a CA 125 test is to monitor the progression of ovarian cancer in women who have already been diagnosed with the disease.

It can also be used to monitor the effectiveness of treatment and to detect any recurrence of the cancer.

In addition to ovarian cancer, the CA 125 test can also be used to monitor other types of cancer, such as endometrial, fallopian tube, and peritoneal cancers, which can also cause elevated CA 125 levels.

The CA 125 test can also be used in women who are at high risk of developing ovarian cancer, such as those with a family history of the disease or those with certain genetic mutations.

In some cases, the CA 125 test may be used in conjunction with other tests, such as transvaginal ultrasound, to help in the early detection of ovarian cancer in women who are at high risk of developing the disease.

What are the Costs of CA 125 test Tests in India?

The cost of a CA 125 test in India can vary depending on the laboratory or healthcare facility where the test is performed.

On average, the cost of a CA 125 test in India ranges from INR 1000 to INR 3000.

Factors that can influence the cost of a CA 125 test in India include the location of the laboratory or healthcare facility, the technology used to perform the test, and whether the test is covered by health insurance.

It is important to check with your healthcare provider or insurance company to determine if the CA 125 test is covered by your health insurance plan.

Some insurance plans may cover the cost of the test if it is deemed medically necessary.

What is the Normal Range and All Values of CA 125 test?

The normal range for CA 125 levels in the blood is typically less than 35 units per milliliter (U/mL). However, it is important to note that the normal range can vary depending on the laboratory where the test is performed.

Below is a table showing the different ranges of CA 125 levels and their meanings:

  • Less than 35 U/mL: Normal
  • 35-50 U/mL: Borderline
  • Greater than 50 U/mL: Elevated

It is important to interpret CA 125 levels in the context of the individual's medical history and other test results. A single CA 125 test result is not sufficient to diagnose ovarian cancer or any other condition.

What Do High CA 125 test Levels Indicate?

High CA 125 levels can indicate a variety of conditions, including ovarian cancer, endometriosis, uterine fibroids, pelvic inflammatory disease, and liver cirrhosis. In some cases, high CA 125 levels may not be related to any underlying medical condition.

In women with ovarian cancer, high CA 125 levels may indicate advanced disease or tumor recurrence. However, it is important to note that not all women with ovarian cancer will have elevated CA 125 levels.

High CA 125 levels can also be caused by non-cancerous conditions, so further testing and evaluation are necessary to determine the underlying cause of the elevated levels.

What Do Low CA 125 test Levels Indicate?

Low CA 125 levels are typically considered normal and do not indicate any underlying medical conditions. However, it is important to note that some women with ovarian cancer may have normal CA 125 levels.

Low CA 125 levels may also be seen in women who are in the early stages of ovarian cancer or in women with certain types of ovarian tumors that do not produce CA 125.

In some cases, low CA 125 levels may be due to factors such as age, pregnancy, menstruation, or the use of certain medications. If low CA 125 levels are detected, further evaluation may be necessary to determine the cause.

In conclusion, the CA 125 test is a valuable tool in the diagnosis and monitoring of ovarian cancer. It is important to interpret CA 125 levels in the context of the individual's medical history and other test results.

If you have any concerns about your CA 125 levels, it is important to consult with your healthcare provider for further evaluation and guidance.